2-PHENYLBENZYL BROMIDE - Names and Identifiers
2-PHENYLBENZYL BROMIDE - Physico-chemical Properties
Molecular Formula | C13H11Br
|
Molar Mass | 247.13 |
Density | 1.353 g/mL at 25 °C (lit.) |
Melting Point | 45-46 °C |
Boling Point | 120-125 °C/0.1 mmHg (lit.) |
Flash Point | >230°F |
Vapor Presure | 1.77E-05mmHg at 25°C |
Storage Condition | Room Temprature |
Refractive Index | n20/D 1.6280(lit.) |
2-PHENYLBENZYL BROMIDE - Risk and Safety
Hazard Symbols | C - Corrosive
|
Risk Codes | 34 - Causes burns
|
Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S27 - Take off immediately all contaminated clothing.
S28 - After contact with skin, wash immediately with plenty of soap-suds.
S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.
|
UN IDs | UN 3265 8/PG 2 |
WGK Germany | 3 |
Hazard Class | 8 |
Packing Group | III |
2-PHENYLBENZYL BROMIDE - Upstream Downstream Industry
2-PHENYLBENZYL BROMIDE - Introduction
2-phenylbenzyl bromide is an organic compound with the chemical formula C14H11Br. It is a colorless or light yellow solid substance with an aromatic taste. The following is a detailed description of the nature, use, preparation and safety information of 2-phenylbenzyl bromide:
Nature:
-Appearance: Colorless or light yellow solid
-Boiling point: About 285 ° C
-Density: about 1.33g/cm³
-Solubility: Slightly soluble in water, soluble in organic solvents such as ethanol and dichloromethane
Use:
2-phenylbenzyl bromide is commonly used as an intermediate in organic synthesis, and its main uses are as follows:
-As the raw material of antiepileptic drugs, it plays an important role in the preparation of phenytoin and other drugs.
-can be used in the synthesis of aromatic ethers, ketones and alcohols and other organic compounds.
-Can be used as an ingredient in surfactants and antibacterial agents.
-It is also used in the preparation of dyes and light stabilizers.
Method:
The preparation method of 2-phenylbenzyl bromide is mainly synthesized by benzylation. A common preparation method is to react benzyl magnesium bromide with acetophenone to produce 2-phenylbenzyl alcohol, which is then brominated to produce 2-phenylbenzyl bromide.
Safety Information:
- 2-phenylbenzyl bromide should be used to prevent contact with skin, eyes and mucous membranes to avoid irritation and injury.
-Wear appropriate personal protective equipment such as protective gloves, glasses and face masks when using.
-Avoid inhaling its vapor or dust, and operate in a well-ventilated place.
-In case of accidental contact or inhalation, rinse immediately with water and seek medical assistance.
-During storage and transportation, keep away from fire and oxidant, avoid violent oscillation and high temperature.
Last Update:2024-04-09 15:17:54